I don't like Google Chrome and I use it only when checking how websites are rendered by its engine. My default browser is Firefox and I don't expect things to change soon.
For those of you who've had problems with font rendering in Chrome, here's three simple steps that should fix most (if not all) of those problems.
1. Type chrome://settings/search#hardware in your address bar and press ENTER
2. Uncheck the box "Use hardware acceleration when available" and restart Chrome
1. Open Chrome
2. Type chrome://flags/#disable-direct-write in your address bar and press ENTER
3. Now, click on "Enable" for that option and restart Chrome
1. Close Chrome
2. Go to Desktop
3. Click on Chrome shortcut with right button and click "Properties"
4. In field "Target" type space and after add /high-dpi-support=1 /force-device-scale-factor=1
-- Must be like this, for example: "C:\Program Files (x86)\Google\Chrome\Application\chrome.exe" /high-dpi-support=1 /force-device-scale-factor=1
5. Now save the changes and start Chrome
I haven't tried step 3 myself, only because the first two settings fixed my problems. Good luck!